The key to manufacturing competitive products and maintaining compliance is effective quality assurance and control in the highly regulated pharmaceutical industry. This is why microorganisms in liquids are quantified by the membrane filtration method. This method allows accurate quantification of bacteria, yeasts and molds when low counts in a high sample volume are anticipated. The method of transferring the membrane filter onto an agar medium is a critical step that can be a source of secondary contamination and lead to false-positive test results. Therefore, it is essential to reduce the risk of exogenous contamination entailed by the use of tweezers to transfer the membrane.
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